盧特康Lutimax主要成份對癌症的預防和治療抗癌，抗突變，抗血管生成的屬性
木犀草素在低微摩爾範圍抑制正常和腫瘤細胞的增殖，以及在體外血管生成。大量新生血管形成的抑制有助於預防某些慢性疾病，包括實體惡性腫瘤的。木犀草素示出針對不同的人類腫瘤細胞系強的抗增殖活性（在某些激素依賴性癌症系如乳腺癌，攝護腺癌，和例如甲狀腺癌）（35,36,37,38,39）。
木犀草素抑制酪氨酸激酶，參與腫瘤細胞增殖的酶。
（46）通過調製的酶，毒性及各種異生素的致癌性可能會受到影響（40）的活性。
木犀草素是一種重要的飲食防癌劑（20,41,42）。一些研究表明，除了木犀草素對大鼠的飲食抑製鹽漬，曬乾，烤和炸食物（43）的誘裂。
木犀草素具有通過減少致癌物的食品中形成如雜環胺，多環芳香族烴和N-亞硝基化合物從前體強的化學預防活性。木犀草素能阻斷致癌物的活化，增加致癌物質的解毒並刺激無誤差DNA修復（43）。
20甲基膽是強誘變劑誘導的纖維肉瘤與之飼餵的小鼠的100％。膳食補充木犀草素20-甲基膽沿著顯示對腫瘤表達一個顯著減少到60％。與在實驗期間（44）的端部的控制相比，腫瘤生長和腫瘤體積下降至85％。
木犀草素具有抗雌激素誘導的乳腺癌（45，46）的潛在抗癌作用。
木犀草素抑制N-二acetlytransferase（參見抗菌）的能力也有關其抗腫瘤特性。木犀草素抑制在人類和小鼠白血病細胞24小時的芳基胺N-乙醯轉移酶活性和DNA
-2-氨基芴加合物的形成。
（47）
木犀草素對顯示一些飲食強有力的抗突變作用
Cancer prevention and treatment
anticarcinogenic, antimutagenic, antiangiogenic properties
Luteolin in the low micromolar range inhibits the proliferation of normal and tumor cells, as well as in vitro angiogenesis. Inhibition of extensive neovascularization can contribute to prevention
of certain chronic diseases, including solid malignancies. Luteolin shows strong antiproliferative activity against different human cancer cell lines (in some hormone-dependent cancer lines such as
breast, prostate, and thyroid cancer for instance) (35,36,37,38,39).
Luteolin inhibits tyrosine kinase, an enzyme involved in tumor cell proliferation. (46) By modulating the activity of enzymes, toxicity and carcinogenicity of various xenobiotics may be affected
(40).
Luteolin is an important dietary cancer preventive agent (20,41,42). Several studies demonstrated that the addition of Luteolin to the diet of rats inhibits the clastogenicity of salted,
sun-dried, broiled and deep-fried food (43).
Luteolin has strong chemopreventive activity by reducing the formation of carcinogens in food such as heterocyclic amines, polycyclic aromatic hydrocarbons and N-nitroso compounds from precursors.
Luteolin is able to block the activation of carcinogens, increase the detoxification of carcinogens and stimulate the error-free DNA repair (43).
20-Methylcholanthrene is a strong mutagen that induces fibrosarcoma in 100% of mice fed with it. Dietary supplementation with Luteolin along with 20-methylcholanthrene showed a significant
reduction on tumor expression to 60 %. The tumor growth and tumor volume decreased to 85 % compared with the control at the end of the experimental period (44).
Luteolin has potential anticarcinogenic effects against estrogen-induced mammary carcinogenesis (45, 46).
The ability of luteolin to inhibit N-acetlytransferase (see section antibacterial) is relevant also for its antineoplastic properties. Luteolin inhibited the arylamine N-acetyltransferase activity
and DNA-2-aminofluorene adduct formation in human and mouse leukemia cells for 24h. (47)
Luteolin displays potent antimutagenic action against some dietary carcinogens (e.g. polychlorinated biphenyl). (48)
